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Proficiency Testing/EQA / Genetics and Molecular Pathology /
Molecular Oncology-Solid Tumors

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SARCOMA FUSION GENE - SARC
SARC
Analytes/procedures in bold type are regulated for proficiency testing by the Centers for Medicare & Medicaid Services (CMS).

Gene Challenges per Shipment Number of Shipments
Sarcoma fusion gene* 3 Two shipments per year


Laboratories performing FISH for sarcoma translocation refer to the Cytogenetics programs.


Program Information

  • Three snap‑frozen cell pellets from which approximately 5.0‑μg of RNA can be extracted
  • For laboratories performing molecular testing using RT-PCR and NanoString

Shipping Schedule

  • Shipment A: May 9
  • Shipment B: November 28

Fusion Gene Listing:
COL1A::PDGFB, t(17;22)
ETV6::NTRK3, t(12;15)
EWSR1::ATF1, t(12;22)
EWSR1::ERG, t(21;22)
EWSR1::FLI1, t(11;22)

EWSR1::FLI1 or EWSRI::ERG
EWSR1::WT1, t(11;22)
FUS::DDIT3, t(12;16)
PAX3::FOXO1, t(2;13)
PAX7::FOXO1, t(1;13)
PAX3::FOXO1 or PAX7::FOXO1
SS18::SSX1, t(X;18)
SS18::SSX2, t(X;18)
SS18::SSX1 or SS18::SSX2





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