Most pregnancies and placental evaluations are within normal ranges and without concern for complications or necessary interventions. Awareness of placental pathologies affecting the mother and infant can explain poor outcomes in the infant, aid in future pregnancies, provide early diagnosis and intervention, and prepare for effective monitoring for the mother and infant. This activity will identify ten perinatal diagnoses: chronic histiocytic intervillositis, massive perivillous fibrin deposition (maternal floor infarct), candida placentitis, CMV placentitis, maternal vascular malperfusion, massive villous edema, inborn errors of metabolism, fetal vascular malperfusion, meconium myonecrosis, and basal plate myometrial fibers. By the end of the activity, attendees will be able to identify symptoms common to each perinatal diagnosis and interventions to help mediate risks in the mother and infant.
This activity was presented at CAP21 as part of the activity Focus on Gynecologic Pathology: Advanced Answers for Daily Practice.
After completing this activity, you should be able to:
- Diagnose maternal and fetal vascular malperfusion in the placenta and know their clinical significance.
- Know critical values in placental diagnoses including candida placentitis and inborn errors of metabolism.
- Identify a differential diagnosis for chronic villitis.
Drucilla J. Roberts, MD, FCAP
Accreditation: The College of American Pathologists (CAP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
CME Category 1: The College of American Pathologists designates this internet enduring material educational activity for a maximum of 1
AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
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College of American Pathologists
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Northfield, IL 60093-2750
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This activity and evaluation are available March 16, 2022, and expire March 14, 2025, at 12:00 AM (ET). You must claim credit by this date and time.