Benign Isn’t Boring: Daily Difficulties in Endometrial Biopsies That Go Beyond Classifying Cancer - GYNNDOBIO03W.2022
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This anatomic pathology activity is intended for pathologists who have basic to moderate knowledge and skills in gynecologic and endometrial pathology.

Credit Type: CME
Duration: 1 hour 15 minutes
Launch Date: March 30, 2022
Expiration Date: March 28, 2025 11:59 PM (CT)
Pricing: Junior Member Fee: $10.00
MOC Category: Medical Knowledge, Patient Care

Endometrial biopsies are routine office procedures that only rarely lead to a diagnosis of cancer. While educational content often focuses on the identification and classification of malignancies, what about the other 90% of our specimens? What are the things that matter and that might be difficult for the general surgical pathologist or early-career subspecialty pathologist to identify?

This interactive course will identify four key areas of benign endometrial pathology that routinely result in questions among colleagues or might prompt sending endometrial biopsies out for consultation. The faculty will use case studies to examine progestin treatment effects, sub-carcinoma-threshold mucinous and papillary surface proliferations of the endometrium, endometrial histiocytic proliferations, and unusual endometrial polyps. By the end of the activity, attendees will know common presentations of each scenario and will be able to identify the common pitfalls in diagnosis.

This activity was presented at CAP21 as Benign Isn’:t Boring: Daily Difficulties in Endometrial Biopsies That Go Beyond Classifying Cancer.

After completing this activity, you should be able to:

  1. Evaluate progestin-treated endometrial biopsies, with or without a history of hyperplasia/carcinoma, conveying the appropriate amount of uncertainty to treating gynecologists.
  2. Classify poorly sampled endometrial mucinous and papillary proliferations into skip-worthy, mildly concerning, and suspicious categories to appropriately guide clinical management.
  3. Recognize the many faces of histiocytic inflammation in the endometrium.
  4. Differentiate histiocytic inflammation in the endometrium from mimics.

Amy Joehlin-Price, MD, MS, FCAP

CME Information
Accreditation: The College of American Pathologists (CAP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CME Category 1: The College of American Pathologists designates this internet enduring material educational activity for a maximum of 1.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Payment Information
To pay with a check, print a copy of this page and send it with your check to the address below. You will be notified when your payment has been processed and you have been registered into the activity.

College of American Pathologists
CAP Learning
325 Waukegan Road
Northfield, IL 60093-2750

Refund Policy
Refunds will be handled on an exception basis. Please submit your request to the CAP in writing via email at or fax at 847-832-8006.

Technical Requirements
Pop-up blockers must be turned off.

The CAP recognizes that some Veteran’s Administration, US Government, and military participants may have difficulty accessing the online activity. If you experience difficulty or have any questions, please contact a representative of the Customer Contact Center at 800-323-4040 option 1 or

This activity and evaluation are available March 30, 2022, and expire March 28, 2025, at 11:59 PM (CT). Upon completion of the activity your credit will be awarded. Your certificate may be downloaded from your Transcript.


Non-Member Price:   $65.00  
Member Price:  $50.00   

Benign Isn’t Boring: Daily Difficulties in Endometrial Biopsies That Go Beyond Classifying Cancer