Neoadjuvant therapy (NAT) is used increasingly in breast carcinoma. This activity will discuss the indications of NAT and important chemotherapeutic regimes. The activity will cover the recommendations of the international working group for assessing post-NAT resection specimens with emphasis on: the proper sampling of post-NAT specimens; estimation of tumor size and residual cancer burden; post-therapy staging issues; and essential components to include in the pathology report. Predictors of pathologic complete response will also be briefly discussed.
This activity was presented at CAP21 as A Roadmap Towards the “Perfect” Pathology Report of Post-Neoadjuvant Therapy Resections.
After completing this activity, you should be able to:
- Correctly gross and stage a post-NAT specimen.
- Calculate residual cancer burden.
- Formulate a complete and concise report on a post-NAT specimen.
Uma Krishnamurti, MD, PhD, FCAP
Marina Mosunjac, MD, FCAP
Accreditation: The College of American Pathologists (CAP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
CME Category 1: The College of American Pathologists designates this internet enduring material educational activity for a maximum of 1.25
AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
To pay with a check, print a copy of this page and send it with your check to the address below. You will be notified when your payment has been processed and you have been registered into the activity.
College of American Pathologists
325 Waukegan Road
Northfield, IL 60093-2750
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This activity and evaluation are available March 21, 2022, and expire March 20, 2025, at 12:00 AM (ET). You must claim credit by this date and time.